Clomicalm is a tricyclic antidepressant (clomipramine) used to treat separation anxiety in dogs. It helps minimize destructive and negative behaviors like vocalization (excessive barking), inappropriate urination and defecation, and moodiness caused by anxiety. It is not a tranquilizer or a sedative, and should not affect your dog's personality or memory.

Common symptoms that Clomicalm treats include:

• Vocalization (excessive barking, whining, or crying)
• Inappropriate urination and defecation
• Moodiness
• Destructive behavior

Conditions that Clomicalm treats include:

• Separation anxiety

Give tablets orally once or twice a day as directed by your veterinarian. To reduce the chance of vomiting, give with a small amount of food.

Dogs 6 months and older

Clomipramine hydrochloride

The most common side effects include vomiting, lethargy, diarrhea, excessive thirst, and decreased appetite. If you’re concerned about any side effects, talk to your vet. If you suspect your dog is having an adverse reaction, seek immediate medical help

Be sure to tell your vet about any medications, vitamins, or supplements that your pet is taking, or if your vet has a history of seizures.