Safety Information

Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines.2

Warnings 

• APOQUEL is not for use in dogs younger than 12 months of age
• APOQUEL modulates the immune system
• APOQUEL is not for use in dogs with serious infections
• APOQUEL may increase susceptibility to infection, including demodicosis, and exacerbation of
• neoplastic conditions
• New neoplastic conditions (benign and malignant) were observed in dogs treated with APOQUEL during clinical studies and have been reported in the post-approval period
• Consider the risks and benefits of treatment prior to initiating APOQUEL in dogs with a history of recurrent serious infections or recurrent demodicosis or neoplasia
• Keep APOQUEL in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.3

Human Warnings

• This product is not intended for human use. Keep this and all drugs out of reach of children. For use in dogs only. Wash hands immediately after handling APOQUEL tablets. In case of accidental eye contact, flush immediately with water or saline for at least 15 minutes, then seek medical attention. In case of accidental ingestion, seek medical attention immediately.1

References

1. DailyMed. "APOQUEL (Oclacitinib Maleate)." National Library of Medicine, National Institutes of Health, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=275a2c51-9679-4f42-b8cc-21b04369a056#:~:text=APOQUEL%20is%20...-,APOQUEL
2. Apoquel.com. "Safety | Apoquel." Zoetis, www.apoquel.com/safety.
3. Zoetis US. "Apoquel Prescribing Information." Zoetis, www.zoetisus.com/content/pages/products/dogs/Apoquel-Resources/documents/apoquel_prescribing_information.pdf